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Why should you switch to primary cells?
Primary cells, directly isolated from source tissues, offer greater physiological relevance for disease modeling, tissue engineering, and regenerative medicine than immortalized cell lines. They better model gene expression, RNA/protein modifications, and cellular processes. Unlike passaged immortalized lines prone to genetic instability, primary cells maintain stability.
How does Amnion address ethical considerations of placental and stem cells?
Amnion Foundation acquires fully consented birth tissue cells, including genetic and -omics testing consent, from vaginal, cesarean section, and full-term births. Our cells retain traditional benefits without moral concerns of embryonic stem cells or age-related degradation of induced pluripotent stem cells. Isolated from the placenta’s fetal side, our cells maintain telomerase activity and long telomeres, maximizing their value.
What are the advantages of placental cells?
Amnion Foundation prioritizes maternal/fetal health, drug discovery, and regenerative medicine through placental cells. Abundant and easily accessible, these cells avoid ethical dilemmas of embryonic stem cells. They encompass multipotency, high telomerase activity, chromosomal stability, and longevity from young donors.
Why is our placental cell isolation process different?
Our cell products derive from on-site placentas obtained within 12 hours of delivery. Tissues undergo decontamination, manual dissection, and enzymatic dissociation. Positive selections on specific markers enrich cell products, followed by rigorous quality checks – density/viability analysis, sterility confirmation, endotoxin/bacterial/fungi/mycoplasma checks, morphology confirmation, and flow cytometry immunophenotype testing. Cell products include CofA and FDA HCT/P-tested donor serologies.